The hypothesis that high TC causes CVD was introduced in the 1960s by the authors of the Framingham Heart Study. However, in their 30-year follow-up study published in 1987, the authors reported that “For each 1 mg/dl (0.02586 mmol/L) drop in TC per year, there was an eleven percent increase in coronary and total mortality”. Three years later the American Heart Association and the US National Heart, Lung and Blood Institute published a joint summary concluding “a one percent reduction in an individual’s TC results in an approximate two percent reduction in CHD risk”. What the...
Besides, multiple high quality nutritional science shows that low-carbohydrate diet is more effective for weight loss and cardiovascular risk factor reduction than the low-fat diet. Here's a Randomized Control Trial study showing exactly that.